Production Of Transgenic Animals Notes

To yield industrial as well as consumer product To research human diseases To produce pharmaceutical products and tissue for implantation.

Production of transgenic animals notes. In addition to the gene itself the DNA usually includes other sequences to enable it to be incorporated into the DNA of the host and to be expressed correctly by the cells of the host. PowerPoint PPT presentation. The three main ways of producing transgenic animals are pronuclear manipulation embryonic stem ES cell manipulation and.

Agricultural Applications a Breeding Farmers have always used selective breeding to produce animals that exhibit desired traits eg. The animals used for transgenic purpose naturally carry the mechanism needed to produce complex protein. Transgene is incorporated into the ES cell by Microinjection By a retro virus By electroporation Transgenic stem cells are grown in vitro.

Applications Of Transgenic Animals. Example- Transgenic rats rabbits pigs sheep etc. Studying gene function.

The medical and biotechnological uses of animal cloning are almost innumerable as many diseases have been eradicated thanks to the production of these transgenic animals. Animals that have had their DNA manipulated to possess and express a foreign gene are known as transgenic animals. Transgenic animals are created-To study how genes are regulated and how they affect the normal functions of the body and its development.

Transgenic animal technologies have come a long way since the creation of the first transgenic mouse in 1974 Transgenic Mouse 2005. The transgenic animals are created because of the benefits they provide to the man. A Gene requires certain cellular mechanism to help for the production of protein.

The foreign genes must be transmitted through the germ line so that every cell including germ cells of the animal contains the same modified genetic material. Many procedures have been developed to increase the efficiency of this generally inefficient process. Transgenic organisms are organisms that are injected with foreign DNA.